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骨关节炎患者关节软骨TIMP—3启动子区甲基化水平的初步研究(3)
http://www.100md.com 2014年1月15日 彭红春 谢明 沈奕 彭丹
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    参见附件。

     [3] Kashiwagi M,Tortorella M,Nagase H,et al.TIMP-3 is a potent inhibitor of aggrecanase 1(ADAM-TS4)and aggrecanase 2(ADAM-TS5)[J].J Biol Chem,2001,276(16):12501-12504.

    [4] Smookler DS,Mohammed FF,Kassiri Z,et al.Tissue inhibitor of metalloproteinase 3 regulates TNF-dependent systemic inflammation[J].J Immunol,2006,176(2):721-725.

    [5] Mahmoodi M,Sahebjam S,Smookler D,et al.Lack of tissue inhibitor of metalloproteinases-3 results in an enhanced inflammatory response in antigen-induced arthritis[J]. Am J Pathol,2005,166(6):1733-1740.

    [6] Arden N,Nevitt MC.Osteoarthritis:epidemiology[J].Best Pract Res Clin Rheumatol,2006,20(1):3-25.

    [7] Hashimoto G,Aoki T,Nakamura H,et al.Inhibition of ADAMTS4(aggrecanase-1)by tissue inhibitors of metalloproteinases(TIMP-1,2,3 and 4)[J].FEBS letters,2001, 494(3):192-195.

    [8] Kevorkian L,Young DA,Darrah C,et al. Expression profiling of metalloproteinases and their inhibitors in cartilage[J].Arthritis Rheum,2004,50(1):131-141.

    [9] Zeng Y,Rosborough RC,Li Y,et al.Temporal and spatial regulation of gene expression mediated by the promoter for the human tissue inhibitor of metalloproteinases-3 (TIMP-3)-encoding gene [J].Dev Dyn,1998,211(3):228-237.

    [10] Zreiqat H,Belluoccio D,Smith MM,et al.S100A8 and S100A9 in experimental osteoarthritis[J].Arthritis Res Ther,2010,12(1):R16.

    [11] Huang Z,Wen Y,Shandilya R,et al.High throughput detection of M6P/IGF2R intronic hypermethylation and LOH in ovarian cancer[J].Nucleic Acids Res,2006,34(2):555-563.

    [12] Kang GH,Lee HJ,Hwang KS,et al.Aberrant CpG island hypermethylation of chronic gastritis,in relation to aging,gender,intestinal metaplasia,and chronic inflammation[J]. Am J Pathol,2003,163(4):1551-1556.

    (收稿日期:2013-08-02 本文编辑:魏玉坡)

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